https://journals.umt.edu.pk/index.php/BSR <p style="text-align: justify;">BioScientific Review (BSR) is an open-access peer-reviewed journal published on a quarterly basis. It provides a modern and multidisciplinary platform for free and fast publications broadly covering all aspects of life sciences. Research in the field of life sciences has grown at a bewildering pace during the last decade and BSR intends to publish momentous advances in all specialized areas of life sciences and bring them to light.&nbsp;</p> en-US <p style="text-align: justify;"><em>BSR</em>&nbsp;follows an open-access publishing policy and full text of all published articles is available free, immediately upon publication of an issue. The journal’s contents are published and distributed under the terms of the&nbsp;<a href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International</a>&nbsp;(<a href="https://creativecommons.org/licenses/by/4.0/">CC-BY 4.0</a>) license. Thus, the work submitted to the journal implies that it is original, unpublished work of the authors (neither published previously nor accepted/under consideration for publication elsewhere). On acceptance of a manuscript for publication, a corresponding author on the behalf of all co-authors of the manuscript will sign and submit a completed&nbsp;the&nbsp;Copyright and Author Consent Form.</p> [email protected] (Dr. M. Sohail Afzal) [email protected] (Syeda Saira Iqbal) Fri, 30 May 2025 00:00:00 +0000 OJS 3.1.2.1 http://blogs.law.harvard.edu/tech/rss 60 https://journals.umt.edu.pk/index.php/BSR/article/view/5910 <p><strong>Background.</strong> Hepatitis C virus (HCV) is a blood-borne infection that has spread all over the world. Around 10 million people in Pakistan are impacted by HCV, while over 58 million people worldwide have a chronic HCV infection. HCV is well known for its severe effects on the liver as well as its extra-hepatic manifestations.</p> <p><strong>Objective.</strong> This study assessed the renal profile (urea and creatinine), hematological factors (Hb, HCT, MCV), and diabetic profile (blood glucose fasting, blood glucose random, and HbA1c) of HCV-positive patients confirmed by real-time PCR (RT-PCR). The main aim was to determine the impact of hepatitis infection.</p> <p><strong>Methodology. </strong>This was a retrospective cohort study conducted on patients diagnosed as HCV-positive by using real-time PCR (RT-PCR). Their diabetic, renal, and hematological association with HCV was observed and analyzed by using SPSS 25.</p> <p><strong>Results.</strong> Out of 296 HCV-positive patients, 174 (58.8%) were male and 122 (41.2%) were female, indicating that HCV was found to be more prevalent in male patients. There was no statistical association found between HbA1c and gender. However, there was found a significant association of blood glucose fasting and blood glucose random with gender. Renal and hematological profiles were also disturbed in HCV-infected individuals.</p> <p><strong>Conclusion.</strong> Health professionals may benefit from this study by managing disrupted profiles more effectively and providing improved patient care. Additional research on the disrupted hematological, renal, and diabetic profiles may improve the treatment conditions for patients since these profiles revealed a variety of extra-hepatic symptoms in this study</p> Tahira Batool, Tahira Idrees, Rukhsar Akbar, Rabbia Mutaqeen, Asma Irshad Copyright (c) 2025 Tahira Batool, Tahira Idrees, Rukhsar Akbar, Rabbia Mutaqeen, Asma Irshad https://creativecommons.org/licenses/by/4.0 https://journals.umt.edu.pk/index.php/BSR/article/view/5910 Sun, 13 Jul 2025 00:00:00 +0000