https://journals.umt.edu.pk/index.php/SIR/issue/feedScientific Inquiry and Review2026-01-20T11:11:43+00:00Dr. Muhammad Ali[email protected]Open Journal Systems<p style="text-align: justify;">Scientific Inquiry and Review is a peer reviewed multidisciplinary journal providing knowledge about the research updates in various fields of science that is published Quarterly. It is a source of authentic information for scientific personnel covering wide range of research aspects.</p>https://journals.umt.edu.pk/index.php/SIR/article/view/7280Significance of Exponential Space-Based Internal Heat Source on Bio-Convective Maxwell Nanofluid Flow Due to Stretching Sheet in the Presence of Darcy–Forchheimer and Lorentz Forces2026-01-20T11:07:21+00:00Muhammad Arbaz Arbaz[email protected]Muhammad Khurshid Azam[email protected]Muhammad Imran[email protected]<p>This study investigates two-dimensional flow of bio-convective Maxwell nanofluid over a stretching sheet in the influence of motile microorganisms. Furthermore, the impact of thermal radiation and exponential space-based heat sources have been analyzed. The results showed that magnetic, Darcy–Forchheimer, Deborah and inertia parameters significantly suppressed the velocity field while modifying thermal and concentration boundary-layer thicknesses. Brownian motion and thermophoretic effects enhanced temperature and nanoparticle concentration, whereas bioconvective parameters strongly regulated microorganism density and associated bio-convective patterns. Applications of the current research study include model oil reservoirs, solar energy technology, re-entry of spacecraft, electrical power generation, cosmological flows, chemical engineering, air and water management systems, industrial zones, human blood flow, bioindustrial systems, environmental sciences and power generating systems, <em>etc</em>.</p>2026-01-20T11:07:21+00:00Copyright (c) 2026 Muhammad Arbaz Arbaz, Muhammad Khurshid Azam, Muhammad Imranhttps://journals.umt.edu.pk/index.php/SIR/article/view/77002025 Nobel Prize: Tregs Unlock Immune Tolerance2026-01-20T11:11:43+00:00Muhammad Shoaib Khan[email protected]<p>The 2025 Nobel Prize in Physiology or Medicine has been awarded to the researchers who identified regulatory T cells, abbreviated as Tregs, a groundbreaking discovery concerning peripheral immune tolerance. These cells protect our body from autoimmune diseases. The fields of immunology and clinical medicine have been influenced by their discoveries. With the increased knowledge of immunology, novel therapeutic strategies for the treatment of allergies, lethal autoimmune diseases, and organ transplant rejection are being introduced. While, targeted therapies to restore immune balance are expected.</p>2025-12-15T00:00:00+00:00Copyright (c) 2026 Muhammad Shoaib Khan