Cubosomes in Drug Delivery: Exploring Their Potential for Advanced Therapeutic Applications

Keywords: cubosomes, monoolein, nanoparticles, poloxamer 407, targeted drug delivery

Abstract

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Cubosomes have become a subject of increasing significance because of their unique three-dimensional nano cubic lattice structure, which is composed of self-assembling lipid molecules like monoolein. A wide range of therapeutic agents, involving both hydrophilic and hydrophobic drugs, can be encapsulated within this stable and water-dispersible structure. Cubosomes' unique cubic lattice also facilitates surface modifications and lipid content adaptation, improving drug stability and resistance to degradation. This enables precise control over the kinetics of drug release and provides an intriguing framework for the development of controlled drug release systems. As a result, cubosomes can improve therapeutic efficacy while minimizing side effects of drugs molecules. In conclusion, this review explores the potential uses of cubosomes and highlights the specifics that emphasize their significance in improving drug delivery methods.

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Published
2025-04-12
How to Cite
Ali, S., Farooq, N., Rehman, S. U., & Rehman, F. U. (2025). Cubosomes in Drug Delivery: Exploring Their Potential for Advanced Therapeutic Applications. Currents in Pharmaceutical Research, 3(2), 01-30. https://doi.org/10.32350/cpr.32.01
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Articles