Prevalence of HCV-Helicobacter pylori co-infection and its effects on liver function enzymes of patients in Lahore, Pakistan

  • Sohaib Bin Wahid Liwah Hospital, Liwa-Madinat Zayed Road, Liwa, Abu Dhabi, United Arab Emirates
  • Muhammad Waqar Genome Centre for Molecular Based Diagnostics and Research, Lahore Pakistan
  • Zobaria Rehman Genome Centre for Molecular Based Diagnostics and Research, Lahore Pakistan
  • Muhammad Wasim Genome Centre for Molecular Based Diagnostics and Research, Lahore Pakistan
  • Muhammad Idrees Genome Centre for Molecular Based Diagnostics and Research, Lahore Pakistan
DOI: https://doi.org/10.32350/BSR.0103.02
Keywords: HCC, hepatotoxicity, HCV, H.pylori

Abstract

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Helicobacter pylori and HCV are the most prevalent pathogens worldwide associated with high rates of morbidity and mortality. This study aimed to determine the prevalence of H. pylori in HCV infected patients and compares changes in liver function tests (LFTs) of both HCV mono-infected and HCV/H. pylori co-infected patients. Eighty-seven participants participated in this study who were first screened for HCV using GeneXpert technology followed by H. pylori antigen stool test. A complete blood count (CBC) analysis and LFTs were performed to determine the impact of HCV and H. pylori on liver enzymes. Our findings suggested that 45% of patients had HCV mono-infection, whereas 55% were co-infected with both HCV and H. pylori. Furthermore, we also observed that ALT, AST, and ALP levels were significantly elevated in HCV/H. pylori co-infected patients as compared to HCV mono-infected patients. To the best of our knowledge, this is the first study to report the prevalence of H. pylori in HCV infected subjects of Lahori population

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Published
2019-09-11
How to Cite
Bin Wahid, S., Waqar, M., Rehman, Z., Wasim, M., & Idrees, M. (2019). Prevalence of HCV-Helicobacter pylori co-infection and its effects on liver function enzymes of patients in Lahore, Pakistan. BioScientific Review, 1(3), 09-14. https://doi.org/10.32350/BSR.0103.02
Issue
Vol 1 No 3 (2019): September
Section
Research Articles

Copyright (c) 2019 Sohaib Bin Wahid, Muhammad Waqar, Zobaria Rehman, Muhammad Wasim, Muhammad Idrees

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