A Cross-Sectional Survey of Vitamin A Deficiency and the Associated Risk Factors among the Children of District Gujrat, Punjab, Pakistan

  • Adil Hussain Department of Biology, Beaconhouse College Programme, Gujrat, Pakistan
  • Safa Rafique Institute of Biochemistry and Biotechnology, University of the Punjab, Pakistan
  • Sana Batool School of Biological Sciences, University of the Punjab, Lahore, Pakistan
  • Saman Hina Department of Biochemistry, NUR International University, Lahore, Pakistan
  • Malik Siddique Mahmood Institute of Biochemistry and Biotechnology, University of the Punjab, Lahore Pakistan https://orcid.org/0000-0002-8007-6843
Keywords: vitamin A deficiency, diet plan, health measures, socioeconomic status

Abstract

Abstract Views: 583

Vitamin A deficiency (VAD) is a very common problem in developing countries and in extreme situations, it is responsible for vision impairment as well as death. To conduct a comprehensive cross-sectional evaluation of the deficiency of vitamin A and the associated risk factors responsible for its deficiency, a questionnaire based survey was conducted in District Gujrat, Punjab, Pakistan. In order to evaluate the data related to VAD and its relationship with different variables, a cross-sectional survey was conducted of 400 female students from three different schools in District Gujrat. The schools were situated in both rural and urban areas. A questionnaire eliciting personal information, family status and diet related information was used to collect the required data for the survey. The results did not pertain with the participants’ gender. The results were based on the summer season routine of diet and physical activity. All information was sorted and the results were analyzed using the Microsoft Excel 2010 update and SPSS version 20. It was found that 39% girls (156 out of 400) were deficient in vitamin A. The main source of VAD was found to be inadequate dietary consumption. It was also found that children with poor socioeconomic standing, low fluid consumption, and from urban areas have more VAD than others. Moreover, the age group of 8-11 years carried a higher percentage of VAD, while physical activity had no impact on VAD. A large number of girls were reported as the victims of VAD due to poverty and related socioeconomic constraints prevailing among the school going children in District Gujrat. A crucial approach towards reducing VAD is to learn about the preventive measures to control VAD. In low-income countries, the use of vitamin A supplements with daily diet is required to reduce the impact of VAD.

Copyright(c) The Authors

Downloads

Download data is not yet available.

References

van Stuijvenberg ME, Dhansay MA, et al. South African preschool children habitually consuming sheep liver and exposed to vitamin a supplementation and fortification have hypervitaminotic a liver stores: a cohort study. Am J Cli Nutr. 2019 Jul 1;110(1):91-101. https://doi.org/10.1093/ajcn/nqy382

Zinder R, Cooley R, Vlad LG, et al. Vitamin A and wound healing. Nutr Cli Practice. 2019 Dec;34(6):839-49. https://doi.org/10.1002/ncp.10420

Miller AP, Coronel J, Amengual J. The role of β-carotene and vitamin A in atherogenesis:evidences from preclinical and clinical studies. Biochim Biophys Acta Bioenerg (BBA)-Mol Cell Biol Lipids. 2020 Jan 21:158635. https://doi.org/10.1016/j.bbalip.2020.158635

Dwyer JT, Coates PM, Smith MJ. Dietary supplements: regulatory challenges and research resources. Nutrients. 2018 Jan;10(1):1-41. https://doi.org/10.3390/nu10010041

Coates PM, et al. Encyclopedia of Dietary Supplements. 2010: Informa Healthcare.

Shils ME, Shike M. Modern Nutrition in Health and Disease. 2006:Lippincott Williams & Wilkins.

Coates PM, Betz JM, Blackman MR, et al., Encyclopedia of Dietary Supplements. 2010:CRC Press.

US Department of Agriculture. USDA National Nutrient Database for Standard Reference. 2013. https://www.ars.usda.gov/

Coates PM, Paul MC, Blackman M, et al. Encyclopedia of Dietary Supplements (Online). 2004 Dec 29:CRC Press.

Bailey RL, Gahche JJ, Lentino CV, et al. Dietary supplement use in the United States, 2003–2006. J Nutr. 2011 Feb 1;141(2):261-6. https://doi.org/10.3945/jn.110.133025

Table M. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. National Academy Press: Washington, DC, USA; 2005. https://doi.org/10.17226/10490

World Health Organization. Global prevalence of vitamin A deficiency in populations at risk 1995-2005: WHO global database on vitamin A deficiency. 2009:1-86.

Yang C, Chen J, Liu Z, et al. Prevalence and influence factors of vitamin A deficiency of Chinese pregnant women. Nutr J. 2015 Dec;15(1):1-7.

Alanazi SA, El-Hiti GA, Al-Baloud AA, et al. Effects of short-term oral vitamin A supplementation on the ocular tear film in patients with dry eye. Clin Ophthalmol (Auckland, NZ). 2019;13:599-604. doi: 10.2147/OPTH.S198349

Sudfeld CR, Navar AM, Halsey NA. Effectiveness of measles vaccination and vitamin a treatment. Int J Epidemiol. 2010 Apr 1;39(suppl_1):i48-55. https://doi.org/10.1093/ije/dyq021

Foster A, Sommer A. Corneal ulceration, measles, and childhood blindness in Tanzania. Brit J Ophthalmol. 1987 May 1;71(5):331-43. http://dx.doi.org/10.1136/bjo.71.5.331

West Jr KP. Extent of vitamin a deficiency among preschool children and women of reproductive age. J Nutr. 2002 Sep 1;132(9):2857S-66S. https://doi.org/10.1093/jn/132.9.2857S

International Institute for Population Sciences. National family health survey (NFHS-3), 2005-06: India. International Institute for Population Sciences; 2007.

Horton S. Opportunities for investments in nutrition in low-income Asia. Asian Development Bank. 1999. http://hdl.handle.net/11540/5393

Akhtar S, Ahmed A, Randhawa MA, et al. Prevalence of vitamin A deficiency in South Asia: causes, outcomes, and possible remedies. J Health Popul Nutr. 2013 Dec;31(4):413-423. doi: 10.3329/jhpn.v31i4.19975

Khan MA, Gilbert C, Khan MD, et al. Incidence of blinding vitamin A deficiency in North West Frontier Province and its adjoining federally administered tribal areas, Pakistan. Ophthalmic Epidemiol. 2009 Jan 1;16(1):2-7. https://doi.org/10.1080/09286580802573185

Rauf S, Sharif N, Hamid A. Serum vitamin A levels in children under five years old. J Ayub Med College Abbottabad. 2002;14(1):26-07.

Sommer A. Vitamin A deficiency and clinical disease: an historical overview. J Nutr. 2008 Oct 1;138(10):1835-9. https://doi.org/10.1093/jn/138.10.1835

Miandad M, Anwar MM, Ahmed S,et al. Assessment of risk factors associated with spread of tuberculosis in Gujrat city Pakistan. Coğrafya Dergisi. 2019(39):41-60. https://doi.org/10.26650/JGEOG2019-0023

Cordeiro A, Bento C, de Matos AC, et al. Vitamin A deficiency is associated with body mass index and body adiposity in women with recommended intake of vitamin A. Nutrición hospitalaria: Organo Oficial De La Sociedad Española De Nutrición Parenteral Y Enteral. 2018;35(5):1072-8.

Rahman S, Rahman AS, Alam N, et al. Vitamin A deficiency and determinants of vitamin A status in Bangladeshi children and women: findings of a national survey. Public Health Nutr. 2017 Apr;20(6):1114-25. https://doi.org/10.1017/S1368980016003049[Opens in a new window]

Bloem MW, Hye A, Wijnroks M, et al. The role of universal distribution of vitamin A capsules in combatting vitamin A deficiency in Bangladesh. Am J Epidemiol. 1995 Oct 15;142(8):843-55. https://doi.org/10.1093/oxfordjournals.aje.a117724

World Health Organization. Xerophthalmia and night blindness for the assessment of clinical vitamin A deficiency in individuals and populations. World Health Organization; 2014:1-6.

Kersting M, Alexy U, Schürmann S. Critical dietary habits in early childhood: principles and practice. Hidden Hunger. 2016;115:24-35. https://doi.org/10.1159/000441885

Martini S, Rizzello A, Corsini I, Romanin B, et al. Vitamin A deficiency due to selective eating as a cause of blindness in a high-income setting. Pediatrics. 2018 Apr 1;141(Supplement 5):S439-44.

Shibata K, Hirose J, Fukuwatari T. Relationship between urinary concentrations of nine water-soluble vitamins and their vitamin intakes in Japanese adult males. Nutr Metabolic Insights. 2014 Jan;7:NMI-S17245. https://doi.org/10.4137/NMI.S17245

Marriott BM. The Effect of Exercise and Heat on Vitamin Requirements, in Nutritional Needs in Hot Environments: Applications for Military Personnel in Field Operations. Washington, DC:National Academy Press;1993:187–214.

Huang Z, Liu Y, Qi G, et al. Role of vitamin A in the immune system. J Cli Med. 2018 Sep;7(9):258-. https://doi.org/10.3390/jcm7090258

Kaminstein D, Kuhn WT, Huang D, et al. Perspectives on Point-of-Care Ultrasound Use in Pediatric Tropical Infectious Disease. Cli Pediatric Emerg Med. 2019 Jun 1;20(2):128-40. https://doi.org/10.1016/j.cpem.2019.06.003

Payne LG, Koski KG, Ortega-Barria E, et al. Benefit of vitamin A supplementation on Ascaris reinfection is less evident in stunted children. Journal Nutr. 2007 Jun 1;137(6):1455-9. https://doi.org/10.1093/jn/137.6.1455

Published
2020-09-17
How to Cite
Hussain, A., Rafique, S., Batool, S., Hina, S., & Mahmood, M. S. (2020). A Cross-Sectional Survey of Vitamin A Deficiency and the Associated Risk Factors among the Children of District Gujrat, Punjab, Pakistan. BioScientific Review, 2(3), 46-59. https://doi.org/10.32350/BSR.0203.05
Section
Research Articles