Development of Chapattis with the Whole Wheat Flour and Fig Leaves for Type II Diabetic Patients
Abstract
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Diabetes is becoming the major cause of morbidity and mortality throughout the world. Its prevalence throughout the Pakistan population is 11.77%. Medicinal plants and herbs are being used since the ancient times to treat diabetes. One of these plants is fig and its several species are being used for maintaining the blood glucose level. It contains many bioactive compounds such as flavonoids, tannins, vitamin E, sterols, and alkaloids etc. which play important role in regulating blood glucose levels. In the following study, chapattis were developed by fortifying whole wheat flour with fig leaves to check its effectiveness in lowering blood glucose level. Sensory evaluation and proximate analysis of the product was done along with the two different compositions used for the product development. Two biochemical tests – fasting blood glucose level and 2-h postprandial blood glucose level were performed on diabetic patients. The obtained data was subjected to appropriate statistical techniques. The results showed that the chapattis with 15 gm of fig leaves were the most appropriate to consume because chapattis with 10 gm of fig leaves were effective but in the long run whereas chapattis with 20 gm of fig leaves had the tendency to put an individual in hypoglycaemic state.
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Khan KY, Khan MA, Ahmad M, Hussain I, Mazari P, Fazal H, Ali B, Khan IZ. Hypoglycemic potential of genus Ficus L.: a review of ten years of plant based medicine used to cure diabetes (2000–2010). J Appl Pharm Sci. 2011;1(06):223-7.
Rahmani AH, Aldebasi YH. Ficus carica and its constituents role in management of diseases. Asian J Pharm Clin Res. 2017;10(6):49-53.
Lukachan D, Poulose AC, Joseph T. Effectiveness of Oral Intake of Fenugreek Seed Powder among Patients with Type 2 Diabetes Mellitus. Int. J Innov Res Develop. 2016;5(14):145-52.
Kaur C, Kapoor HC. Antioxidants in fruits and vegetables–the millennium’s health. Int J Food Sci Tech. 2001;36(7):703-25.
Meo SA, Zia I, Bukhari IA, Arain SA. Type 2 diabetes mellitus in Pakistan: Current prevalence and future forecast. JPMA. J Pak Med Assoc. 2016;66(12):1637-42.
Aamir AH, Ul-Haq Z, Mahar SA, Qureshi FM, Ahmad I, Jawa A, Sheikh A, Raza A, Fazid S, Jadoon Z, Ishtiaq O. Diabetes Prevalence Survey of Pakistan (DPS-PAK): prevalence of type 2 diabetes mellitus and prediabetes using HbA1c: a population-based survey from Pakistan. BMJ open. 2019;9(2):e025300.
Patil VV, Patil VR. Evaluation of anti-inflammatory activity of Ficus carica Linn. leaves. Indian J Nat Prod Resour. 2011;2:151–155.
Stephen Irudayaraj S, Christudas S, Antony S, Duraipandiyan V, Naif Abdullah AD, Ignacimuthu S. Protective effects of Ficus carica leaves on glucose and lipids levels, carbohydrate metabolism enzymes and β-
cells in type 2 diabetic rats. Pharma Bio. 2017;55(1):1074-81.
Atkinson FS, Villar A, Mulà A, Zangara A, Risco E, Smidt CR, Hontecillas R, Leber A, Bassaganya-Riera J. Abscisic acid standardized fig (Ficus carica) extracts ameliorate postprandial glycemic and insulinemic responses in healthy adults. Nutr. 2019;11(8):1757.
Zhang Y, Chen J, Zeng Y, Huang D, Xu Q. Involvement of AMPK activation in the inhibition of hepatic gluconeogenesis by Ficus carica leaf extract in diabetic mice and HepG2 cells. Biomedi Pharma. 2019;109:188-94.
Ajmal M, Arshad MU, Saeed F, Ahmed T, Khan AU, Bader-ul-Ain H, Suleria HA. Exploring The Nutritional Characteristics of Different Parts of Fig in Relation to Hypoglycemic Potential. Pak J Life Social Sci. 2016;14(2):1727-4915.
Mohammadi H, Karimifar M, Heidari Z, Zare M, Amani R. The effects of wheat germ supplementation on metabolic profile in patients with type 2 diabetes mellitus: A randomized, double‐blind, placebo‐ controlled trial. Phyto Res. 2020;34(4):879-85.
Reynolds AN, Mann J, Elbalshy M, Mete E, Robinson C, Oey I, Silcock P, Downes N, Perry T, Te Morenga L. Wholegrain particle size influences postprandial glycemia in type 2 diabetes: a randomized crossover study comparing four wholegrain breads. Diabetes Care. 2020;43(2):476-9.
AOAC. Official methods of analysis of association of official analytical chemists international. In:Horwitz, W. 20th ed. AOAC Press, Arlington, VA, USA; 2016.
Lim J, Wood A, Green BG. Derivation and evaluation of a labeled hedonic scale. Chem Senses. 2009;34(9):739-51.
AOAC. Official methods of analysis, 18th ed. Association of Official Analytical Chemists. Arlington, 2006; USA.
AOAC. Official methods of analysis, 18th ed. Association of Official Analytical Chemists. Arlington, Virginia, USA; 2007.
Hasan AN, Roy NJ, Bristy SK, Paul TB, Wahed, Alam MN. Evaluation of in vitro antioxidant and brine shrimp lethality bioassay of different
extracts of Polygonum plebeium R. British Int J. 2015;3:97-107.
Chang CC, Yang MH, Wen HM, Chern JC. Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J Food Drug Analy. 2002;10(3):178-182.
Ahmad S, Bhatti FR, Khaliq FH, Irshad S, Madni A. A review on the prosperous phytochemical and pharmacological effects of Ficus carica. Int J Bioassays. 2013;2(5):843-9.
Famurewa A, Folawiyo A, Epete M, Onuoha M, Igwe E. Consumption of caffeinated energy drink induces alterations in lipid profile and hepatic aminotransferases in experimental rats. J Chem Pharm Res. 2015;7:363-9.
Idrus RB, Sainik NQ, Ansari AS, Zulfarina MS, Razali RA, Nordin A, Saim AB, Naina-Mohamed I. Ficus carica and bone health: A systematic review. Sains Malaysiana. 2018;47(11):2741-55.
El Dessouky Abdel-Aziz M, Samir Darwish M, Mohamed AH, El- Khateeb AY, Hamed SE. Potential activity of aqueous fig leaves extract, olive leaves extract and their mixture as natural preservatives to extend the shelf life of pasteurized buffalo milk. Foods. 2022;9(5):615.
Stone H, Sidel JL. Introduction to sensory evaluation. Sensory Evaluation Practices (Third Edition). Academic Press, San Diego. 2004:1-9.
Gillani M, Iftikhar H, Lodhi A, Pasha I. Development and characterisation of fig (Ficus carica) leaves tea with special reference to hypoglycemic effect. Biological Sciences-PJSIR. 2018;61(2):78-83.
Serraclara A, Hawkins F, Perez C, Domınguez E, Campillo JE, Torres MD. Hypoglycemic action of an oral fig-leaf decoction in type-I diabetic patients. Diabetes Res Clin Prac. 1998;39(1):19-22.
Meilgaard M, Civille GV, Carr BT. Overall difference tests: does a sensory difference exist between samples. Sensory evaluation techniques. 2007;4:63-104.
Amerine MA, Pangborn RM, Roessler EB. Principles of sensory evaluation of food. Elsevier; 2013.
