2025 Nobel Prize: Tregs Unlock Immune Tolerance
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The 2025 Nobel Prize in Physiology or Medicine has been awarded to the researchers who identified regulatory T cells, abbreviated as Tregs, a groundbreaking discovery concerning peripheral immune tolerance. These cells protect our body from autoimmune diseases. The fields of immunology and clinical medicine have been influenced by their discoveries. With the increased knowledge of immunology, novel therapeutic strategies for the treatment of allergies, lethal autoimmune diseases, and organ transplant rejection are being introduced. While, targeted therapies to restore immune balance are expected.
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References
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It reviews the biology, molecular regulation, and clinical significance of regulatory T cells, emphasizing their central role in human immune-mediated diseases.
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Copyright (c) 2026 Muhammad Shoaib Khan
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