Evaluation of Pre- and Post-operative Nutritional Status of Gastrointestinal Surgery Patients
DOI:
https://doi.org/10.32350/ihr.61.02Keywords:
anthropometric and biochemical indicators, gastrointestinal surgery, malnutrition, nutritional assessment, postoperative outcomesAbstract
Malnutrition is highly prevalent in patients undergoing gastrointestinal (GI) surgeries, and is associated with adverse health outcomes. Both pre- and post-operative nutritional status assessment of these patients may help timely diagnose and manage health complications. The current study aimed to assess the nutritional status of GI surgery patients both before and after surgery and then determined associations between both values. The study was a prospective observational cohort one that utilized convenience sampling to collect data from 75 GI surgery patients admitted in a local tertiary care settings. Data was collected on socio-demographics, anthropometric and biochemical parameters, as well as clinical signs and symptoms. Paired t-test was used to assess associations after data was analyzed on SPSS version 23. Approximately, 52% of the study sample comprised males and 32.2% patients had undergone cholelithiasis surgery. White blood cells (WBCs) (p = 0.000) and lymphocyte count (p = 0.015) were both statistically significant for pre- and post-operative associations. However, Body Mass Index (BMI), hemoglobin, hematocrit, and creatinine levels were not found to be statistically significant. Malnutrition is common among those with GI issues and surgeries. Nutrition assessment prior to surgery and timely nutrition interventions can help prevent and manage complications arising from poor nutritional status in these patients.
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1. Emerenini FC, Nwolisa EC, Iregbu FU, Eke CB, Ikefuna AN. Prevalence and risk factors for Helicobacter pylori infection among children in Owerri, Nigeria. Niger J Clin Pract. 2021;24(8):1188-1193. https://doi.org/10.4103/njcp.njcp_687_20
2. Fikree A, Byrne P. Management of functional gastrointestinal disorders. Clin Med (Lond). 2021;21(1):44-52. https://doi.org/10.7861/clinmed.2020-0980
3. Vaou N, Zavras N, Saldari C, et al. Post-surgical gut microbiota alterations in pediatric patients with intestinal disorders. J Clin Med. 2026;15(2):e789. https://doi.org/10.3390/jcm15020789
4. Kenny E, Samavat H, Touger-Decker R, Parrott JS, Byham-Gray L, August DA. Adverse perioperative outcomes among patients undergoing gastrointestinal cancer surgery: quantifying attributable risk from malnutrition. JPEN J Parenter Enteral Nutr. 2022;46(3):517-525. https://doi.org/10.1002/jpen.2200
5. Serón-Arbeloa C, Labarta-Monzón L, Puzo-Foncillas J, et al. Malnutrition screening and assessment. Nutrients. 2022;14(12):e2392. https://doi.org/10.3390/nu14122392
6. Eminovic S, Vincze G, Eglseer D, et al. Malnutrition as predictor of poor outcome after total hip arthroplasty. Int Orthop. 2021;45(1):51-56. https://doi.org/10.1007/s00264-020-04892-4
7. Keerio RB, Ali M, Shah KA, Iqbal A, Mehmood A, Iqbal S. Evaluating the impact of preoperative nutritional status on surgical outcomes and public health implications in general surgery patients. Cureus. 2024;16(12):e76633. https://doi.org/10.7759/cureus.76633
8. Vinarov Z, Abdallah M, Agundez JA, et al. Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: an UNGAP review. Eur J Pharm Sci. 2021;162:105812. https://doi.org/10.1016/j.ejps.2021.105812
9. Noorian S, Kwaan MR, Jaffe N, Yaceczko SD, Chau LW. Perioperative nutrition for gastrointestinal surgery: on the cutting edge. Nutr Clin Pract. 2023;38(3):539-556. https://doi.org/10.1002/ncp.10970
10. Deftereos I, Yeung JMC, Arslan J, et al. Assessment of nutritional status and nutrition impact symptoms in patients undergoing resection for upper gastrointestinal cancer: Results from the multicentre NOURISH point prevalence study. Nutrients. 2021;13(10):e3349. https://doi.org/10.3390/nu13103349
11. Karanikki E, Frountzas M, Lidoriki I, et al. The predictive role of preoperative malnutrition assessment in postoperative outcomes of patients undergoing surgery due to gastrointestinal cancer: a cross-sectional observational study. J Clin Med. 2024;13(23):e7479. https://doi.org/10.3390/jcm13237479
12. Jones D, Knight SR, Sremanakova J, et al. Malnutrition and nutritional screening in patients undergoing surgery in low- and middle-income countries: a systematic review. JCSM Clin Rep. 2022;7(4):79-92. https://doi.org/10.1002/crt2.55
13. Morales F, Montserrat-de la Paz S, Leon MJ, Rivero-Pino F. Effects of malnutrition on the immune system and infection and the role of nutritional strategies regarding improvements in children's health status: a literature review. Nutrients. 2023;16(1):e1. https://doi.org/10.3390/nu16010001
14. Liu J, Hu J, Fang J, et al. Risk factors of esophagojejunal anastomotic leakage after total gastrectomy for gastric and Siewert type II/III esophagogastric cancer: A retrospective analysis from a tertiary hospital. Front Oncol. 2024;14:e1481278. https://doi.org/10.3389/fonc.2024.1481278
15. Lobo DN, Gianotti L, Adiamah A, et al. Perioperative nutrition: recommendations from the ESPEN expert group. Clin Nutr. 2020;39(11):3211-3227. https://doi.org/10.1016/j.clnu.2020.03.038
16. Simancas-Racines D, Frias-Toral E, Campuzano-Donoso M, et al. Preoperative nutrition in bariatric surgery: a narrative review on enhancing surgical success and patient outcomes. Nutrients. 2025;17(3):e566. https://doi.org/10.3390/nu17030566
17. Jaxa-Kwiatkowski A, Jaxa-Kwiatkowski M, Jaxa-Kwiatkowska K, Gerber H, Kubiak M, Łysenko L. Perioperative nutritional and metabolic factors affecting surgical outcomes in head and neck cancer free flap reconstruction: a comprehensive review. J Clin Med. 2025;14(11):e3679. https://doi.org/10.3390/jcm14113679
18. Liu S, Huang H, Zhang C, et al. Postoperative leukocyte counts as a surrogate for surgical stress response in matched robot- and video-assisted thoracoscopic surgery cohorts of patients: a preliminary report. J Robot Surg. 2024;18(1):e176. https://doi.org/10.1007/s11701-024-01939-1
19. Elbromboly Y, Esawy MA. Post-operative C-reactive protein and white blood cells changes pattern following spinal deformity surgery and its clinical correlation. J Orthop Surg Res. 2023;18(1):e790. https://doi.org/10.1186/s13018-023-04288-1
20. Hildenborg M, Kåhlin J, Granath F, et al. The neuroimmune response to surgery: an exploratory study of trauma-induced changes in innate immunity and heart rate variability. Front Immunol. 2022;13:e911744. https://doi.org/10.3389/fimmu.2022.911744
21. Schoenberg MB, Han Y, Li X, et al. Dynamics of peripheral blood immune cells during the perioperative period after digestive system resections: a systematic analysis of the literature. J Clin Med. 2023;12(2):e718. https://doi.org/10.3390/jcm12020718
22. Jiang Y, Zhao Z, Lu H, Zhou L. Association between bariatric surgery and anemia. Nutr Clin Métab. 2022;36(3):217-224. https://doi.org/10.1016/j.nupar.2022.07.004
23. Jungwirth-Weinberger A, Bendich I, Westrich GH, Su EP, Della Valle AG, Boettner F. Preoperative ferritin and hemoglobin levels are lower in patients with a history of COVID-19 but blood loss and transfusion requirements are not increased. Arch Orthop Trauma Surg. 2023;143(1):311-315. https://doi.org/10.1007/s00402-021-04082-w
24. Acharya K, Rout DK, Kapadia NA, et al. Surgical stress response: a physiological review of the endocrine, immune, and metabolic changes. Cureus. 2025;17(12):e100101. https://doi.org/10.7759/cureus.100101
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Copyright (c) 2026 Zoha Imtiaz Malik, Syed Hassan Bin Usman Shah, Aisha Ijaz Ul Haq, Abdul Momin Rizwan Ahmad

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