Prevalence of ABO and Rh Blood Groups and Their Association with Transfusion-Transmissible Infections (TTIs) among Blood Donors in Islamabad, Pakistan
Abstract
Abstract Views: 308
Certain Rh positive blood groups showed a link between the ABO blood grouping and susceptibility to some infectious ailments. Study was carried out to find the association of ABO Blood Group System / Rh type with different viral infection. A retrospective observational study was carried in 7631 blood donors to find the association of ABO Blood Group System / Rh type with viral infection due to hepatitis B virus, hepatitis C virus, human immunodeficiency virus and Syphilis. Data of the study indicateF that the highest incidence of blood group in blood donor was B followed by O, A and AB. The incidence of HBsAg +ve, HCV Ab +ve and infection of Syphilis was also highest in donor with blood group B followed by O, A and AB. Blood group A were more susceptible to HIV Ab +ve followed by blood group B, O and AB. The group B donors had the greatest risk of viral infection with HBV, HCV, HIV, and Syphilis; followed by the groups O, A, and AB. Donors in group AB had the lowest incidence rate of all viral infection. The study revealed that blood group B is most prevalent among donors, followed by blood groups O, A, and AB. On the other side, the rate of HBV, HCV, HIV, and Syphilis infection was greatest among group B donors, followed by group O, group A, and group AB.
Keywords: ABO Blood Group System, hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), syphilis
Copyright(c) The Authors
Downloads
References
Fan Q, Zhang W, Li B, Li D-J, Zhang J and Zhao F. Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan. Front. Cell. Infect. Microbiol.2020; 10:404. doi: 10.3389/fcimb.2020.00404
Cooling L. Blood Groups in Infection and Host Susceptibility. Clin Microbiol Rev. 2015;28(3):801-870. doi:10.1128/CMR.00109-14
Nicholson LB. The immune system. Essays Biochem. 2016;60 (3):275-301. doi:10.1042/EBC20160017
Groot HE, Laura E, Sierra V, Said MA, Lipsic E, and Karper JC et al. Genetically Determined ABO Blood Group and its Associations with Health and Disease. Arteros, Thromb, and Vas Biol 2020; 40(3): 830-83 doi.org/10.1161/ATVBAHA.119.313658
Mäkivuokko H, Lahtinen SJ, Wacklin P, Tuovinen E, Tenkanen H, Nikkilä J, et al. Association between the ABO blood group and the human intestinal microbiota composition. BMC Microbiol 2012;12:94. doi:10.1186/1471-2180-12-94
Dong Y, Qiu C, Xia X, Wang J, Zhang H, Zhang X, et al. Hepatitis B virus and hepatitis C virus infection among HIV-1-infected injection drug users in Dali, China: prevalence and infection status in a cross-sectional study. Arch Virol. 2015; 160(4): 929–936. doi.org/10.1007/s00705-014-2311-0 PMID: 25616842
Weldemhret L. Epidemiology and Challenges of HBV/HIV Co-Infection amongst HIV-Infected Donors in Endemic Areas: Review. HIV/AIDS – Res & Palliative Care2021;13:485-490
Wali A, Khan D, Safdar N, Shawani, Fatima R, Yaqoob A et al. Prevalence of tuberculosis, HIV/AIDS, and hepatitis; in a prison of Balochistan: a cross-sectional survey. BMC Public Health 2019; 19:1631doi.org/10.1186/s12889-019-8011-7
Samo AA, Laghari ZA, Baig NM, Khoso GM. Prevalence and Risk Factors Associated with Hepatitis B and C in Nawab shah, Sindh, Pakistan. The Am J Trop Med & Hyg 2020; 104(3):1101-1105 doi.org/10.4269/ajtmh.20-1228
Alqahtani SA, Colombo M. Viral hepatitis as a risk factor for the development of hepatocellular carcinoma. Hepatoma Res 2020; 6:58.10.20517/2394-5079.2020.49
Gedefie A, Adamu A, Alemayehu E, Kassa Y, Belete MA. Hepatitis C Virus Infection among HIV-Infected Donors Attending Dessie Referral Hospital, Northeastern Ethiopia. Int J Microbio Volume 2021, Article ID 6675851, 7 pages https://doi.org/10.1155/2021/6675851
Tsuboi M, Evans J, Davies EP, Roweley J, Korenromp EL, Clayton PT. Prevalence of Syphilis among men who have sex with men: a global systematic review and meta-analysis from 2000–20. Lancet Glob Health 2021; 9(8):e1110-e1118doi.org/10.1016/ S2214-109 X (21)00221-7.
Yosuf R, Abdul Ghani SA, Abdul Khalid M and Chooi Fun LM. Study on ABO and Rh D blood grouping: Comparison between conventional tile method and a new solid phase method (InTec Blood Grouping Test Kit) Malaysian J Pathol 2018; 40(1) : 27 – 32
Thio CL, Smeaton L, Saulynas M, Hwang H, Saravan S, Kulkarni S, et al. Characterization of HIV-HBV coinfection in a multinational HIV-infected cohort. AIDS. 2013; 27(2): 191–201. doi.org/10.1097/ QAD.0b013e32835a9984
Agarwal N, Thapliyal RM, Chatterjee K. Blood group phenotype frequencies in blood donors from a tertiary care hospital in north India. Blood Res. 2013;48(1):51-54. doi:10.5045/br.2013.48.1.51
Islam F, Robert H. Frequency of ABO and Rhesus blood groups in the population of Gilgit area of Pakistan. Pak J Path 2010; 21(3):87-9.
Christ-Dominique, Ngassaki-Yoka, Jophrette Mireille Ntsame Ndong, Cyrille Bisseye, (2018) “ABO, Rhesus blood groups and transfusion-transmitted infections among blood donors in Gabon, Sudan J Med Sci 2018; 13(1): 12–21. doi 10.18502/sjms.v13i1.1685
Garg P, Upadhyay, S, Chufal SS, Hasan Y and Tayal I. “Prevalance of ABO and Rhesus Blood Groups in Blood Donors: A Study from a Tertiary Care Teaching Hospital of Kumaon Region of Uttarakhand”, J Clin & Diag Res 2014; 8(12): FC16-9, 2014.
Farhud DD, Zarif Yeganeh M. A brief history of human blood groups. Iran J Public Health. 2013;42(1):1-6.
Maulot-Bangola D. Nkoa T1, Rebienot P O, Mangala C, Moundanga M, Boussougou O et al. Prevalence and risk factors of Hepatitis B virus infection among blood donors in Gabonese National Blood Transfusion Center: A cross-sectional and analytic study. Int J Med and Medicine Sci 2021;13(1):5-12 DOI: 10.5897/IJMMS2021.1455
Silva CMd, Peder LDd, Guelere AM, Horvath JD, Silva ES, Teixeira JJV, et al. (2018) Seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) among human immunodeficiency virus (HIV)-infected donors in an HBV endemic area in Brazil. PLoS ONE 13(9): e0203272. https://doi.org/10.1371/journal. pone.0203272
Jing W, Zhao S, Liu J, Liu M. ABO blood groups and hepatitis B virus infection: a systematic review and meta-analysis. BMJ Open. 2020;10(1):e034114. doi:10.1136/bmjopen-2019-034114
Batool Z, Durrani SH, Tariq S. Association Of Abo And Rh Blood Group Types To Hepatitis B, Hepatitis C, HIV And Syphilis Infection, A Five Year' Experience In Healthy Blood Donors In A Tertiary Care Hospital. J Ayub Med Coll Abbottabad. 2017 Jan-Mar;29(1):90-92.
Al-Jooani OAA, Al-Hayani AA, Mohammed MJ. The infection with HBV and HCV and their relationship to ABO blood group among blood donors. Fac Med Baghdad2012; 54 (1):52-56
Naseri Z, Ghannad MS, Hosseini S, Roshanaei G, Nejad ASM, Mohammad A. Evaluation of Accompaniment of ABO Blood Groups System and Rhesus blood group types with Infection to Hepatitis B Virus and Hepatitis C Virus in Hamadan, Iran. Int J Med Res & Health Sci 2016; 5(4):1-5
Patwardhan VV, Bhattar S, Bhalla P, Rawat D. Seroprevalence of Syphilis by Syphilis test and biological false positive reactions in different patient populations: Is it alarming? Our experience from a tertiary care center in India. Indian J Sex Transm Dis AIDS. 2020 Jan-Jun;41(1):43-46. doi: 10.4103/0253-7184.194317
Gu X, Gao Y, Yan Y, et al. The importance of proper and prompt treatment of ocular Syphilis: a lesson from permanent vision loss in 52 eyes. J Eur Acad Dermatol Venereol. 2020; 34(7):1569-1578. doi:10.1111/jdv.16347
Nayak S, Acharjya B. Syphilis test and its interpretation. Indian J Dermatol. 2012; 57(1):3-8. doi:10.4103/0019-5154.92666
Copyright (c) 2021 Muhammad Yousaf Khan, Farwa Sijjeel, Ahmareen Khalid, Rukhshan Khurshid, Umm E Habiba, Hina Majid, Mashal Naeem, Basharat Nawaz, Basharat Nawaz, Safdar Abbas, Noor Ul Ain Malik
This work is licensed under a Creative Commons Attribution 4.0 International License.
BSR follows an open-access publishing policy and full text of all published articles is available free, immediately upon publication of an issue. The journal’s contents are published and distributed under the terms of the Creative Commons Attribution 4.0 International (CC-BY 4.0) license. Thus, the work submitted to the journal implies that it is original, unpublished work of the authors (neither published previously nor accepted/under consideration for publication elsewhere). On acceptance of a manuscript for publication, a corresponding author on the behalf of all co-authors of the manuscript will sign and submit a completed the Copyright and Author Consent Form.
